Margaret attended the first public high school in Beckley. After graduation in 1921 she enrolled in Marshall University and later graduated from Concord College with a lifetime Normal Certificate. She began teaching at the age of 17 and taught for 48 years, 31 of them at Crab Orchard. She also taught at Mabscott and Teel. She was the first woman elected president of the Raleigh County Board of Education Association. She was a member of the Mabscott Baptist Church and later became a member of the First Baptist Church of Beckley.
Margaret helped with many organizations including Wildwood Museum, The Friends of the Library, Raleigh County Historical Society, Beckley Concert Association and the Red Cross.
She was preceded in death by her parents, David Ross and Mamie Farley Sullivan; brother, Sidney Sullivan and by two sisters, Loraine Dunham and Christine Souder.